Tetrahedron

The guttiferones, HIV-inhibitory benzophenones from Symphoniaglobulifera, Garcinialivingstonei, Garciniaovalifolia and Clusiarosea

…, RW Fuller, TC McKee, JH Cardellina, JB McMahon…

文献索引：Gustafson, Kirk R.; Blunt, John W.; Munro, Murray H. G.; Fuller, Richard W.; McKee, Tawnya C.; Cardellina II, John H.; McMahon, James B.; Cragg, Gordon M.; Boyd, Michael R. Tetrahedron, 1992 , vol. 48, # 46 p. 10093 - 10102

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被引用次数: 249

摘要

Extracts from species of the tropical plant genera Symphonia, Garcinia and Clusia (Guttiferae) have yielded a series of new polyisoprenylated benzophenone derivatives named guttiferones A–E (1–5). Structural assignments were based on detailed spectral analysis. These compounds inhibit the cytophatic effects of in vitro HIV infection.