Bioorganic chemistry

Synthesis of sulfanilamide derivatives and investigation of in vitro inhibitory activities and antimicrobial and physical properties

H Turkmen, G Zengin, B Buyukkircali

文献索引：Turkmen, Hasan; Zengin, Gulay; Buyukkircali, Belkis Bioorganic Chemistry, 2011 , vol. 39, # 3 p. 114 - 119

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被引用次数: 13

摘要

Novel sulfanilamide derivatives were synthesized and evaluated for carbonic anhydrase inhibitory activity as a target for the treatment of glaucoma, and antibacterial properties for use in chemotherapy. Synthesized compounds were characterized by FT-IR, 1H NMR, 13C NMR and photoluminescence. In vitro inhibitory activities were measured by UV–Vis and some of the compounds were found have greater inhibitory effects than the lead ...