Abstract Research into the reactivity of carbonyl-substituted spirohydrochromans with hydrogen sulfide under the influence of protic and aprotic acids was continued for the case of 3, 4, 5, 6, 7, 8-hexahydrospiro [chromene-2, 1′-cyclohexan]-2-one. The general nature of the reactions was established. Complexes of copper (II) with substituted hydro (thio) chromans were obtained. The results from investigation of the antiphage activity of the ...