Synthesis of substituted-benzyl and sugar-modified analogues of 6-N-(4-nitrobenzyl) adenosine and their interactions with “ES” nucleoside transport systems

…, J Asakura, M Kaneko, S Shibuya…

文献索引：Robins; Asakura; Kaneko; Shibuya; Jakobs; Agbanyo; Cass; Paterson Nucleosides and Nucleotides, 1994 , vol. 13, # 6-7 p. 1627 - 1646

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被引用次数: 15

摘要

Abstract Four classes of 6-X-benzylated purine nucleosides,(i) 6-N-(substituted-benzyl) adenosines,(ii) 6-N-(4-nitrobenzyl) adenine nucleosides with modified sugars,(iii) 6-N (S)-(4- azidobenzyl) derivatives of adenosine, 6-thioinosine, and 6-thioguanosine, and (iv) 6-N-{4-N- [acyl (sulfonyl) amino] benzyl} adenosines, were synthesized and their binding interactions with “es-NT”(e quilibrative, inhibitor-sensitive nucleoside transport) systems were studied. ...