Synthesis of 8, 9??dialkoxy??substituted tetrahydrobenz [h] isoquinolines

KY Zee??Cheng, WH Nyberg…

文献索引：Zee-Cheng,K.Y. et al. Journal of Heterocyclic Chemistry, 1972 , vol. 9, p. 805 - 811

被引用次数: 7

摘要

Abstract 6, 7-Dimethoxy-2-naphthylethylamine, prepared by the diborane reduction of 6, 7- dimethoxy-2-naphtlialeneacetamide, underwent a Pictet-Spengler cyclization to form 8, 9- dimethoxy-1, 2, 3, 4-tetrahydrobenz [h] isoquinoline. This compound is identical with that obtained by reduction of the corresponding dihydrobenzisoquinoline prepared from formamide cyclization. 6, 7-Dialkoxy-2-naphthaleneacetic acids, the key intermediates for ...