Abstract Reaction of 1-nitro-4-(1, 2, 3-triazolyl/tetrazolyl) benzenes with arylacetonitriles in an alcoholic medium in the presence of excess alkali gives novel 2, 1-benzisoxazoles. These findings indicate a high reactivity of nitroarenes activated by the azole ring due to their electron-deficient character. Moreover, it was found that annulation of the isoxazole ring occurred regioselectively in disubstituted nitroarenes. In the case of 1-(4-nitrophenyl)-1H- ...
