J. Chem. Soc., Perkin Trans. 1

Preparation of 14-nitrocamptothecin derivatives by reactions of camptothecin with nitronium tetrafluoroborate in acidic solvents

Z Cao

文献索引：Cao, Zhisong Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 21 p. 2629 - 2632

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被引用次数: 7

摘要

The new camptothecin derivatives (20)-20--acetyl-14-nitrocamptothecin 7 and 5-hydroxy-14- nitrocamptothecin 8 are prepared by the reactions of camptothecin 1 with nitronium tetrafluoroborate 9 in acetic anhydride and trifluoroacetic acid, respectively. When acetic