Microwave assisted synthesis, characterization of some new isatin and thiophene derivatives as cytotoxic and chemopreventive agents

K Gangarapu, S Manda, S Thota…

文献索引：Gangarapu, Kiran; Manda, Sarangapani; Thota, Sreekanth; Yerra, Rajeshwar; Karki, Subhas S.; Balzarini, Jan; De Clercq, Erik; Tokuda, Harukuni Letters in Drug Design and Discovery, 2012 , vol. 9, # 10 p. 934 - 941

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被引用次数: 9

摘要

In obtaining some new cytotoxic and chemopreventive agents with potent antiproliferative activity against cancer cells, a series of new β-isatin aldehyde-N, N'-thiocarbohydrazone, bis- β-isatin thiocarbohydrazones, bis-β-isatin carbohydrazones, N, 2-bis (thiophen-2- ylmethylidene) thiocarbohydrazone and N, 2-bis (thiophen-2-ylmethylidene) carbohydrazone derivatives was synthesized by microwave oriented reaction and ...