Studies on the kinetics of racemization of 2, 4-disubstituted-5 (4 H)-oxazolones

M Slebioda, MA St-Amand, FMF Chen…

文献索引：Slebioda, Marek; St-Amand, Marc A.; Chen, Francis M. F.; Benoiton, N. Leo Canadian Journal of Chemistry, 1988 , vol. 66, p. 2540 - 2544

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被引用次数: 16

摘要

The kinetics of racemization of 2, 4-disubstituted-5 (4 H)-oxazolones obtained from N-acetyl, N-benzoyl, and N-benzyloxycarbonylglycyl-l-leucine,-valine, and-phenylalanine have been studied in several solvents alone and in the presence of tertiary amines. The influence of the nature of the substituents on the rate of the reaction has been evaluated, and the values of the activation parameters Δ H≠ and Δ S≠ for the base-catalyzed reactions have been ...