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The Journal of Organic Chemistry

Preparation of cyanoformates. Crown ether phase transfer catalysis

ME Childs, WP Weber

文献索引:Childs,M.E.; Weber,W.P. Journal of Organic Chemistry, 1976 , vol. 41, p. 3486 - 3487

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被引用次数: 70

摘要

The apparent lack of interest in this class of compounds may be due to difficulty in their synthesis. Benzyl, methyl, and ethyl cyanoformates have been prepared (-30% yield) by reaction of the corresponding alkyl chloroformates with powdered sodium~ yanide.~ Far better yields (70-90%) have been reported for the reaction of carbonyl cyanide with a wide va-