Chiral synthesis via organoboranes. 10. Preparation of. alpha.-chiral acyclic ketones of exceptionally high enantiomeric excess from optically pure borinic esters

HC Brown, M Srebnik, RK Bakshi…

文献索引：Brown,H.C.; Srebnik,M.; Bakshi,R.K. Journal of the American Chemical Society, 1987 , vol. 109, p. 5420

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被引用次数: 44

摘要

Abstract: Optically pure borinic esters, R* R'BOR”, obtained from optically pure boronic esters, R* B (OR'') 2 and organolithium reagents, were treated with dichloromethyl methyl ether (DCME) in the presence of lithium tert-butoxide to give, after oxidation with hydrogen ...