Silylations with bis (trimethylsilyl) acetamide, a highly reactive silyl donor

JF Klebe, H Finkbeiner, DM White

文献索引：Klebe,J.F. et al. Journal of the American Chemical Society, 1966 , vol. 88, p. 3390 - 3395

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被引用次数: 368

摘要

Abstract: Silyl-proton exchange reactions with bis (trimethylsily1) acetamide proceed rapidly and quantitatively under mild conditions. The preparative silylation of amides, ureas, and amino acids, as well as hindered phenols, carboxylic acids, and enols, is described. Examples of silylation as a protective measure and a means of preparing reactive intermediates are included. he quantitative conversion of organic compounds T to stable, ...