Azaserine, a New Tumor-inhibitory Substance. Structural Studies. 1

SA Fusari, TH Haskell, RP Frohardt…

文献索引：Fusari et al. Journal of the American Chemical Society, 1954 , vol. 76, p. 2881,2882

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被引用次数: 56

摘要

, Iji 13. TV~ enliaus and HZ ich. Uti., 65B, NI i I fI< j321 about 50%. The barium salt of N- diazoacetyl-L-serine (11) was isolated as a crude yellow-green powder, Et,%. 448 at X 252 mp (pH 7.0). A paper chromatographic strip run on this material gave two very faint ninhydrin zones indicating relatively complete migration with a small amount of hydrolysis to free serine. This salt possessed little or no microbiological activity.