Synthesis of several compounds related to 1-(4-methylsulfonylphenacyl)-4-phenylpiperazine and their pharmacological screening

…, V Bártl, E Svátek, M Protiva

文献索引：Vejdelek; Bartl; Svatek; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 7 p. 1498 - 1506

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摘要

Abstract The title compound I was transformed to its oxime II, hydrazone III and semicarbazone IV. 1-(4-Methylsulfonylphenyl)-2-(4-phenylpiperazino) ethanol (V) was esterified by the corresponding acid chlorides in pyridine to give the acetate VI, propionate VII, benzoate VIII, and 4-nitrobenzoate IX. Reactions of 4-(methylsulfonyl) phenacyl bromide, its 4-(ethylsulfonyl), and 4-(2-methylpropylsulfonyl) analogues with diethanolamine ...