Chemistry–An Asian Journal

A Highly Efficient Friedel–Crafts Reaction of Tertiary α??Hydroxyesters or α??Hydroxyketones to α??Quaternary Esters or Ketones

L Chen, J Zhou

文献索引：Chen, Long; Zhou, Jian Chemistry - An Asian Journal, 2012 , vol. 7, # 11 p. 2510 - 2515,6

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被引用次数: 1

摘要

The acid-catalyzed Friedel–Crafts reaction of alcohols and electron-rich aromatic compounds is a highly atom-efficient method for the preparation of aromatic compounds with diverse applications, and only water is generated as the byproduct.[1, 2] During the past decade, significant progress has been made in the development of a catalytic version of this transformation, including the construction of hindered allcarbon quaternary centers.[1, 3] ...