Molecules

Investigating the spectrum of biological activity of substituted quinoline-2-carboxamides and their isosteres

…, A Coffey, P Kollar, A Imramovsky, L Placek, J Jampilek

文献索引：Gonec, Tomas; Bobal, Pavel; Sujan, Josef; Pesko, Matus; Guo, Jiahui; Kralova, Katarina; Pavlacka, Lenka; Vesely, Libor; Kreckova, Eva; Kos, Jiri; Coffey, Aidan; Kollar, Peter; Imramovsky, Ales; Placek, Lukas; Jampilek, Josef Molecules, 2012 , vol. 17, # 1 p. 613 - 644

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被引用次数: 26

摘要

Abstract In this study, a series of thirty-five substituted quinoline-2-carboxamides and thirty- three substituted naphthalene-2-carboxamides were prepared and characterized. They were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four mycobacterial species. N- ...