European Journal of Organic Chemistry

Arylation of 8??Acetoxyoctalenone in a Nickel??Catalyzed Coupling Reaction with Lithium Arylborates

Y Kobayashi, M Ito

文献索引：Kobayashi, Yuichi; Ito, Michiko European Journal of Organic Chemistry, 2000 , # 20 p. 3393 - 3397

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被引用次数: 8

摘要

Abstract In order to find a suitable organometallic compound and a catalyst for the arylation of 8-acetoxyoctalenone 4 (a stereoisomeric mixture of 4α and 4β), phenylation was first investigated with PhZnX (7: X= Cl; 8: X= Br)/Pd or Ni cat., PhSnBu 3 (9)/Pd cat. and LiCl, and [PhB (Bu)(OCHMeCHMeO)] Li (10a)/Ni cat. Borate 10a provided the desired product 11a with high stereoselectivity. The stereochemical outcome was irrespective of the ...