A selective receptor for arginine derivatives in aqueous media. Energetic consequences of salt bridges that are highly exposed to water

…, S Mecozzi, K Russell, DA Dougherty

文献索引：Ngola, Sarah M.; Kearney, Patrick C.; Mecozzi, Sandro; Russell, Keith; Dougherty, Dennis A. Journal of the American Chemical Society, 1999 , vol. 121, # 6 p. 1192 - 1201

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被引用次数: 122

摘要

Quantitative measures of salt-bridge-type interactions in a highly exposed aqueous environment have been obtained by modifying the well-studied cyclophane platform 1 to include carboxylates in close proximity to bound, cationic guests, producing hosts 2 and 3. Many guests show significantly enhanced binding to 2 and 3, but cations of the RNMe3+ type show little or no enhancement. We propose that the latter observations result from the ...