The influence of nuclear chlorine and bromine on the chemical and pharmacological properties of amines of the pressor type has engaged the attention of several investigators. Zeynek'prepared both 3, 5-dichloro-and 3, 5-dibromotyramine. Glynn and Linnel12 prepared w-amin0-3~ 4-dichloroacetophenone as well as 3, 4-dichlorophenyl-P-aminoethanol and reported for the latter substance a pressor effect much smaller than that of epinephrine but ...
