Organic letters

Ruthenium-Catalyzed Arylation of 2-Alkenylpyridines with Aryl Bromides: Alternative E, Z-Selectivity to Mizoroki-Heck Reaction

S Oi, K Sakai, Y Inoue

文献索引：Oi, Shuichi; Sakai, Kaori; Inoue, Yoshio Organic Letters, 2005 , vol. 7, # 18 p. 4009 - 4011

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被引用次数: 80

摘要

Regio-and stereoselective arylation of 2-alkenylpyridines with aryl bromides is catalyzed by specific Ru (II)-phosphine complexes affording β-arylated (Z)-2-alkenylpyridines, in which the aryl moiety is introduced cis to the pyridyl group. This geometrical selectivity is in sharp contrast to the Mizoroki-Heck reaction.