Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling

S Duan, D Place, HH Perfect, ND Ide…

文献索引：Suttle, Nicola A.; Williams, Andrew Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 9 p. 1369 - 1372

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... Select a Journal or Book. ... Article ASAP. DOI: 10.1021/acs.oprd.6b00070. Publication Date (Web): May 12, 2016. Copyright © 2016 American Chemical Society. *E-mail ... the discovery chemistry route is highly convergent, and the last two steps had good chemical conversions. ...