On the purpose of searching for the structure–activity relationship (SAR) and obtaining novel anti-platelet drugs, 41 4-methoxybenzene-1, 3-isophthalamides have been described the synthesis process and in vitro activities on anti-platelet aggregation. The target compounds have been classified into four series: series 1 (ortho-substituted phenyl: 1a–1j), series 2 (meta-substituted phenyl: 2a–2k), series 3 (para-substituted phenyl: 3a–3l) and series 4 ( ...
