Tetrahedron letters

An efficient synthesis of sterically hindered arylboronic acids

H Fang, G Kaur, J Yan, B Wang

文献索引：Fang, Hao; Kaur, Gurpreet; Yan, Jun; Wang, Binghe Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1671 - 1674

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被引用次数: 43

摘要

Boronic acids are important intermediates and molecular recognition moieties in a wide variety of applications. In our research, we have found that the synthesis of ortho-substituted arylboronic acids is problematic with the commonly used bis (pinacolato) diboron in palladium-mediated borylation reactions. As a substitute, we have found that bis (neopentyl glycolato) diboron is a much more efficient borylation agent for the synthesis of sterically ...