. alpha.-Adrenoreceptor reagents. 1. Synthesis of some 1, 4-benzodioxans as selective presynaptic. alpha. 2-adrenoreceptor antagonists and potential …

CB Chapleo, PL Myers, RCM Butler…

文献索引：Journal of Medicinal Chemistry, , vol. 26, # 6 p. 823 - 831

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被引用次数: 85

摘要

... Two obvious chemical variations of the RX 781094 structure lead to the synthesis of compound 66, the open-chain analogue (Scheme IV), and 2-(1,4-benzo- dioxan-2-ylmethy1)imidazoline (54).11 The imidazole 65 was prepared ... Journal of Medicinal Chemistry, 1983, Vol. ...