Tetrahedron

Synthetic studies on prehispanolone and 14, 15-dihydroprehispanolone

ES Wang, YM Choy, HNC Wong

文献索引：Wang, En Si; Choy, Yuen Min; Wong, Henry N. C. Tetrahedron, 1996 , vol. 52, # 37 p. 12137 - 12158

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被引用次数: 33

摘要

Employing an intramolecular Michael addition as a pivotal step, butenolide 5, furans 6 and 7 have been converted to dioxaspiro compounds 8, 9, 10 and 11, whose heterocyclic frameworks constitute important structural units of prehispanolone (2) as well as 14, 15- dihydroprehispanolones (3) and (4), respectively. Hispanolone (1) was converted to 2, 3 and 4 by utilizing a similar strategy.