2, 2, 2-Trichloro-N-({2-[2-(dimethylamino) ethyl]-1, 3-dioxo-2, 3-dihydro-1 H-benzo [de] isoquinolin-5-yl} carbamoyl) acetamide (UNBS3157), a Novel Nonhematotoxic …

E Van Quaquebeke, T Mahieu, P Dumont…

文献索引：Journal of Medicinal Chemistry, , vol. 50, # 17 p. 4122 - 4134

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被引用次数: 107

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The synthesis of amonafide (1) was carried out according to a two-step process given in Figure 1. figure Figure 1 The two-step reaction to obtain the synthon amonafide (1 ...