Phosphorescence imaging of living cells with amino acid-functionalized tris (2-phenylpyridine) iridium (III) complexes

P Steunenberg, A Ruggi, NS van den Berg…

文献索引：Steunenberg, Peter; Ruggi, Albert; Van Den Berg, Nynke S.; Buckle, Tessa; Kuil, Joeri; Van Leeuwen, Fijs W.B.; Velders, Aldrik H. Inorganic Chemistry, 2012 , vol. 51, # 4 p. 2105 - 2114

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被引用次数: 34

摘要

A series of luminescent fully cyclometalated octahedral iridium (III) 2-phenylpyridine complexes functionalized with three different amino acids, on one, two, or all three of the phenylpyridine ligands has been synthesized and characterized. Cellular uptake and localization have been studied with flow cytometry and confocal microscopy, respectively. The monosubstituted iridium (III) complexes gave the highest cellular uptake, and the ...