Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide

AB Smith, BS Freeze, MJ LaMarche, T Hirose…

文献索引：Organic Letters, , vol. 7, # 2 p. 311 - 314

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被引用次数: 36

摘要

... Volume: Page: Digital Object Identifier (DOI). ... Organic Letters. ... Table 2. Cytotoxicity Observed for Analogues 21−25. cytotoxicity IC 50 , nM. MCF-7, NCI/ADR, A549, SKOV-3. (+)-1, 28, 240, 22, 21. (+)-4, 5.6, 463, 8.6, 3.4. (+)-21, 5.6, 260, 9.4, 7.6. ...