Journal of the American Chemical Society

Dicarboxylic Acid Bis-β-tertiaryaminoalkyl Amides and their Quaternary Ammonium Salts as Curare Substitutes. II1

AP Phillips

文献索引：Phillips Journal of the American Chemical Society, 1951 , vol. 73, p. 5822

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被引用次数: 2

摘要

A recent preliminary report'presented a few bis-6-tertiaryaminoethyl amides of aliphatic dicarboxylic acids which had been made and found to prolong the duration of the block of neuromuscular transmission produced by diacetylcholine2 in the cat. This paper presents the results of the more complete study of these series with regard to variation in chain length and its effect upon activity for the aminoamides studied. The compounds described can be ...