Discovery of novel aminoquinazolin-7-yl 6, 7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

KH Huang, TE Barta, JW Rice, ED Smith…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 7 p. 2550 - 2554

全文：HTML全文

被引用次数: 9

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 10, 11, 12, 13 and 14 Here we report our synthetic and medicinal chemistry efforts in the discovery of a ... and lower dihydro indolone moieties have been utilized in marketed drugs, for example, the anti-cancer medicine Erlotinib and anti ...