The Journal of Organic Chemistry

Organopalladium approaches to prostaglandins. 3. Synthesis of bicyclic and tricyclic 7-oxaprostaglandin endoperoxide analogs via oxypalladation of norbornadiene

RC Larock, DR Leach

文献索引：Larock, Richard C.; Leach, Douglas R. Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2144 - 2148

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被引用次数: 20

摘要

Prostaglandins in which a methylene unit has been replaced by an oxygen have received considerable attention. A number of 7-oxa analogues of the primary prostaglandins have been synthesized and they exhibit substantial biological More recently attention has turned to prostaglandin endoperoxide analogues in which either the 9, ll-endoperoxide linkage contains only one oxygen atom, 7-13 such as compound 1, or the C-10 position has h