Tetrahedron letters

Metal oxide in aqueous organic solution promoted chemoselective N-sulfonylation of hydrophilic amino alcohols

HH Kang, HS Rho, DH Kim, SG Oh

文献索引：Kang, Hak Hee; Rho, Ho Sik; Kim, Duck Hee; Oh, Seong-Geun Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7225 - 7227

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被引用次数: 10

摘要

The reaction of hydrophilic amino alcohols with sulfonyl chlorides in the presence of metal oxide (MgO, CuO, Ag2O) in aqueous organic solution cleanly provided alkanolsulfonamide. Advantages of this method were mild, neutral reaction conditions, chemoselectivity and easy