Phytochemistry

Polygonolide, an isocoumarin from Polygonum hydropiper possessing anti-inflammatory activity

T Furuta, Y Fukuyama, Y Asakawa

文献索引：Furuta, Takuya; Fukuyama, Yoshiyasu; Asakawa, Yoshinori Phytochemistry (Elsevier), 1986 , vol. 25, # 2 p. 517 - 520

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被引用次数: 73

摘要

Abstract A new isocoumarin polygonolide which inhibits the reversed passive Arthus reaction has been isolated from the methanol extract of the root of Polygonum hydropiper. The structure of polygonolide has been elucidated on the basis of spectroscopic data and confirmed to be 3, 4-dimethyl-6-methoxy-8-hydroxyisocoumarin by total synthesis.