Pyrido [2, 1-b] quinazolinecarboxylic acids as orally active antiallergy agents

…, RA LeMahieu, M Carson, RW Kierstead…

文献索引：Tilley; LeMahieu; Carson; Kierstead; Baruth; Yaremko Journal of Medicinal Chemistry, 1980 , vol. 23, # 1 p. 92 - 95

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被引用次数: 22

摘要

A series of 8-substituted pyrido [2, 1-b] quinazoline-2-carboxylic acids was prepared by the nickel carbonyl mediated carboxylation of the corresponding bromides. The activities of these compounds in the rat PCA test are comparable to those of the corresponding 2- substituted pyrido [2, 1-b] quinazoline-8-carboxylic acids.