Palladium??Catalyzed Alkoxycarbonylation of Terminal Alkenes To Produce α, β??Unsaturated Esters: The Key Role of Acetonitrile as a Ligand

…, N Derrien, M Barłóg, P Kočovský

文献索引：Malkov, Andrei V.; Derrien, Nolwenn; Barlog, Maciej; Kocovsky, Pavel Chemistry - A European Journal, 2014 , vol. 20, # 16 p. 4542 - 4547

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被引用次数: 8

摘要

Abstract A mild protocol has been developed for the Pd II-catalyzed alkoxycarbonylation of terminal olefins to produce α, β-unsaturated esters with a wide range of substrates. Key features are the use of MeCN as solvent (and/or ligand) to control the reactivity of the intermediate Pd complexes and the combination of CO with O 2, which facilitates the Cu II- mediated reoxidation of the Pd 0 complex to Pd II and prevents double carbonylation.