Double Elimination Protocol for Synthesis of 5, 6, 11, 12??Tetradehydrodibenzo [a, e] cyclooctene

…, D Hasegawa, T Nakano, J Otera

文献索引：Orita, Akihiro; Hasegawa, Daiki; Nakano, Takehiko; Otera, Junzo Chemistry - A European Journal, 2002 , vol. 8, # 9 p. 2000 - 2004

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被引用次数: 51

摘要

Abstract A new method for constructing 5, 6, 11, 12-tetradehydrodibenzo [a, e] cyclooctene is described on the basis of one-pot double elimination protocol. The target molecule, which is the smallest cyclophane with alternate arylene− ethynylene linkage, is synthesized in 61% yield through oxidative dimerization of ortho-(phenylsulfonylmethyl) benzaldehyde. The initial carbon–carbon bond formation between sp 3 carbons followed by stepwise ...