Hypotensive 1, 2, 4-Benzothiadiazines

BA Bierbaum, JJ Traverso…

文献索引：Bierbaum,B.A. et al. J. Med. Chem., 1963 , vol. 6, p. 272 - 275

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被引用次数: 15

摘要

: uid di-placrmeiit of the chloiwic oi 2-chloro-3-carboxp-tjtiizt~ iit. iulfoiiaiiiidc yicldrtl thr 2-~ niiiio~~ ciizciic~~ ilfoiiiiiiiio~~ c~ ii~ ci~~ s~ ilf~~ iia~ iiidc~ with i oi inic acid, triethyl oi thoforiiiatc, triethyl ortho-acctatc. mid TI ith tmthyl orthopropioilate yielded 3-I€-,: i-iiiethyl-aiid. i-eth~ ll, 2, ll~ eii~ othiadaziiie-l, l-diox-idrs ('l'ahlc 11) 11ixed aiihydixides of trifluoroacetic: id I\ ith alkaiir. aralkaiie aiid c~ cloalkaiircarboxylic