Rhodium (I)–sulfonated-bdpp catalysed asymmetric hydrogenation of imines in aqueous–organic two-phase solvent systems

…, Á Orosz, B Heil, M Laghmari, P Lhoste…

文献索引：Bakos, Jozsef; Orosz, Arpad; Heil, Balint; Laghmari, Mohamed; Lhoste, Paul; Sinou, Denis Journal of the Chemical Society, Chemical Communications, 1991 , # 23 p. 1684 - 1685

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被引用次数: 83

摘要

Catalytic asymmetric hydrogenation of prochiral alkenes' and ketones2 has been extensively investigated and various homogeneous catalysts have been found to be efficient in the asymmetric hydrogenation of imines.3-5 In this paper we present the first example of asymmetric catalytic hydrogenation of imines in a two-phase system using a water-soluble catalyst to give secondary amines with almost complete enantioselectivity [>go% enantiomeric excess (e . e . )] .6 ...