Synthesis of 2-Deoxy-β-D-ribonucleosides and 2, 3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells

…, H Dvořáková, J Günter, D Hocková…

文献索引：Votruba, Ivan; Holy, Antonin; Dvorakova, Hana; Guenter, Jaroslav; Hockova, Dana; et al. Collection of Czechoslovak Chemical Communications, 1994 , vol. 59, # 10 p. 2303 - 2330

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被引用次数: 29

摘要

Abstract Alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli catalyze the transfer of 2-deoxy-D-ribofuranosyl moiety of 2'-deoxyuridine to purine and pyrimidine bases as well as their aza and deaza analogs. All experiments invariably gave β- anomers; in most cases, the reaction was regiospecific, affording N 9-isomers in the purine and N 1-isomers in the pyrimidine series. Also a 2, 3-dideoxynucleoside can serve as ...