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Tetrahedron

Use of lithium N, O-dimethylhydroxylamide as an efficient in situ protecting agent for aromatic aldehydes

F Roschangar, JC Brown, BE Cooley, MJ Sharp…

文献索引:Roschangar, Frank; Brown, Jennifer C; Cooley Jr., Bobby E; Sharp, Matthew J; Matsuoka, Richard T Tetrahedron, 2002 , vol. 58, # 9 p. 1657 - 1666

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被引用次数: 26

摘要

The use of lithium N, O-dimethylhydroxylamide as an alternative in situ protecting agent for aryl aldehydes with low ortho-directing properties has been evaluated and subsequently applied to two practical multi-step one-pot syntheses of developmental drug candidate intermediates.