Practical synthetic routes to carbon-substituted nucleosides

…, X Zhang, D Leese, R Glen, J Hart, N Forrest, T Guyot

文献索引：Pryde, David C.; Middleton, Donald S.; Stephenson, Peter T.; Wainwright, Philip; Maddaford, Adrian; Zhang, Xiurong; Leese, David; Glen, Rebecca; Hart, James; Forrest, Neil; Guyot, Thierry Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6415 - 6419

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被引用次数: 8

摘要

Robust practical routes to three different carbon-substituted nucleosides are described. Short synthetic procedures for preparing 1′-homonucleosides, 2′-C-methyl- carbanucleosides and 2′-C-methyl-cyclopropyl/cyclopentyl fused bicyclic ribose analogues are described starting from readily available building blocks.