Science

Amine (imine) diphosphine iron catalysts for asymmetric transfer hydrogenation of ketones and imines

W Zuo, AJ Lough, YF Li, RH Morris

文献索引：Zuo, Weiwei; Lough, Alan J.; Li, Young Feng; Morris, Robert H. Science, 2013 , vol. 342, # 6162 p. 1080 - 1083

全文：HTML全文

被引用次数: 153

摘要

Abstract A rational approach is needed to design hydrogenation catalysts that make use of Earth-abundant elements to replace the rare elements such as ruthenium, rhodium, and palladium that are traditionally used. Here, we validate a prior mechanistic hypothesis that partially saturated amine (imine) diphosphine ligands (P-NH-NP) activate iron to catalyze the asymmetric reduction of the polar bonds of ketones and imines to valuable ...