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Concise synthesis of azacycloundecenes using ring-closing metathesis (RCM)

…, C Kato, H Kaneko, A Nishida, M Nakagawa

文献索引:Arisawa, Mitsuhiro; Kato, Chiaki; Kaneko, Hiroaki; Nishida, Atsushi; Nakagawa, Masako Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 12 p. 1873 - 1876

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被引用次数: 2

摘要

Manzamines are a class of cytotoxic β-carboline alkaloids that were isolated from Okinawan marine sponges by Higa and co-workers. Manzamine C 1 is the simplest congener and bears an unprecedented azacycloundecene ring. 1 The total synthesis of 1 was first achieved by one of us [hair space] 2 and afterwards by Gerlach's group [hair space] 3a and by Langlois' group [hair space] 3b using their own original methods. In the original ...