Mechanism of the Rhodium (III)-Catalyzed Arylation of Imines via C–H Bond Functionalization: Inhibition by Substrate

…, AL Rheingold, RG Bergman, JA Ellman

文献索引：Tsai, Andy S.; Tauchert, Michael E.; Bergman, Robert G.; Ellman, Jonathan A. Journal of the American Chemical Society, 2011 , vol. 133, # 5 p. 1248 - 1250

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被引用次数: 107

摘要

Rh (III)-catalyzed arylation of imines provides a new method for C–C bond formation while simultaneously introducing an α-branched amine as a functional group. This detailed mechanistic study provides insights for the rational future development of this new reaction. Relevant intermediate Rh (III) complexes have been isolated and characterized, and their reactivities in stoichiometric reactions with relevant substrates have been monitored. The ...