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Formamide as the amine component in the mannich??type condensation with sulfinic acids and aldehydes

T Olijnsma, J Engberts, J Strating

文献索引:Olijnsma,T. et al. Recueil des Travaux Chimiques des Pays-Bas, 1972 , vol. 91, p. 209 - 212

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被引用次数: 14

摘要

There have been many reports of Mannich-type condensation reactions involving carboxamides as the acidic~ omponent'.~. In contrast, the use of carboxamides as the amine component is subject to a number of limitations and usually the desired amidomethylation products are obtained only via isolation of N-(hydroxymethyl) carboxamides4. However, carboxamides do react as the amine component with sulfinic acids and aldehydes leading ...