Benzylation of arenes through FeCl 3-catalyzed Friedel–Crafts reaction via C–O activation of benzyl ether

…, SK Xiang, ZP Sun, BT Guan, P Hu, KQ Zhao, ZJ Shi

文献索引：Wang, Bi-Qin; Xiang, Shi-Kai; Sun, Zuo-Peng; Guan, Bing-Tao; Hu, Ping; Zhao, Ke-Qing; Shi, Zhang-Jie Tetrahedron Letters, 2008 , vol. 49, # 27 p. 4310 - 4312

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被引用次数: 40

摘要

Various benzyl ethers were converted to benzyl arenes via a FeCl3-catalyzed Friedel–Crafts alkylation reaction under mild condition in good yields. This method also offered a simple and practical approach to synthesize di-or tri-aryl methanes and aryl heteroaryl methanes through the activation of C–O bonds.