TMSCl??Mediated Catalytic Carbocupration of Alkynoates: An Unprecedented and Remarkable Effect of Catalyst Loading on Highly Selective Stereochemical …

MP Jennings, KB Sawant

文献索引：Jennings, Michael P.; Sawant, Kailas B. European Journal of Organic Chemistry, 2004 , # 15 p. 3201 - 3204

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被引用次数: 9

摘要

Abstract The TMSCl-mediated catalytic carbocupration of alkynoates has been investigated. It has been shown that catalyst loadings as low as 30 mol% readily allow for high yields and diastereoselectivities for a series of Grignard reagents. In addition, an unprecedented and remarkable effect of catalyst loading on stereochemical induction has been observed.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)