Structure–activity relationships in Toll-like receptor 7 agonistic 1 H-imidazo [4, 5-c] pyridines

E Yoo, BM Crall, R Balakrishna, SS Malladi…

文献索引：Organic and Biomolecular Chemistry, , vol. 11, # 38 p. 6526 - 6545

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被引用次数: 17

摘要

... M. Fox , Alec R. Hermanson and Sunil A. David * Department of Medicinal Chemistry, University of ... currently known small molecule agonists of TLR7 occupy a very small chemical space, and ... The organic layer was dried using sodium sulfate and evaporated and purified using ...