Tetrahedron: Asymmetry

Enantiomeric excess determination of α-amino acids by 19 F NMR spectroscopy of their N, N-dimethyl-(2, 2, 2-trifluoro-1-phenylethyl) amine-C, N) palladium …

F Levrat, H Stoeckli-Evans, N Engel

文献索引：Levrat, Fabrice; Stoeckli-Evans, Helen; Engel, Norbert Tetrahedron Asymmetry, 2002 , vol. 13, # 21 p. 2335 - 2344

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被引用次数: 25

摘要

The synthesis and resolution of the trifluoromethyl-palladacycle, di-μ-chloro-bis (N, N- dimethyl-(2, 2, 2-trifluoro-1-phenylethyl) amine-2-C, N) palladium (II) are shown. The utility of the complex and its application in the enantiomeric excess determination of α-amino acids by 19F NMR spectroscopy is demonstrated and X-ray diffraction analysis of one of the diastereomeric complexes, trans-{[(R)-phenylglycinato-N, O][(R)-N, N-dimethyl-(2, 2, 2- ...