Development of a pilot scale process for the anti-Alzheimer drug (-)-galanthamine using large-scale phenolic oxidative coupling and crystallisation-induced chiral …
B Küenburg, L Czollner, J Fröhlich…
文献索引：Organic Process Research and Development, , vol. 3, # 6 p. 425 - 431
... AG, Landeggerstrasse 7, A-2491 Neufeld, Austria, and Institute of Organic Chemistry, Vienna ... effect of variations on reaction times and reaction temperatures on process throughput. ... A consistently reproducible procedure has been developed for the crystallisation-induced chiral ...
